Anna is a town situated in Collin County within the state of Texas in the United States.

After the Civil War in America, the Houston and Texas Central Railway restarted constructing tracks north from Corsicana and crossed the region in 1872. When Anna was officially planned in 1883, it already had 20 residents, two shops, a steam-powered gristmill, and a Baptist church. Additionally, a post office was established during the same year. In 1885, a train station was constructed by the railway.

The community was named in tribute to Anna Quinlan, the beloved daughter of George A. Quinlan, who served as the superintendent of the Houston and Texas Central Railroad.

In 1846, Liberty Christian Church was established in northern Collin County, Texas, by courageous pioneers Collin McKinney and J. B. Wilmeth, who were among the first to spread the teachings of the Christian Church (Disciples of Christ) in the Lone Star State.

In approximately 1853, Lewis and Pauline Sherley relocated from Kentucky to north Texas. The grandsons of Lewis and Pauline, Andrew and William Sherley, established a hardware store in 1894.

On May 9, 2006, a severe storm system brought not one, but two tornadoes to Anna, Texas. The first twister, classified as an F0, narrowly missed the high school and the city limits, passing just 2.5 miles to the east. The second tornado, a more powerful F3, wreaked havoc in nearby Westminster and Whitewright, leveling homes and claiming three lives. In the midst of the chaos, dedicated volunteers from Collin County Amateur Radio Services joined forces with the National Weather Service, providing crucial support through a Skywarn net. Meanwhile, the Anna police and fire departments, along with the American Red Cross, opened up Anna High School as a shelter for those affected by the storm, offering refuge to those stranded by road blockages and damage.

Anna is situated in the northern part of Collin County at coordinates 33°21′01″N 96°33′03″W. The U.S. Route 75 highway runs along the western side of the city, connecting it to Dallas, located 45 miles (72 km) to the southwest, and Denison, located 32 miles (51 km) to the north.

According to the 2020 US census, the city was home to 16,896 individuals, 4,450 households, and 3,792 families.

Prominent individuals include Ralph Fults, who was an outlaw linked to the Barrow gang and lived from 1911 to 1993, Curley Johnson, an American football athlete who passed away in 2016 at the age of 81, and Kewpie Morgan, an American silent film comic known from 1892 to 1956.